Potential drug interactions in intensive care unit adult of a public state hospital
Abstract
OBJECTIVE: To identify potential drug interactions in adult intensive care unit of a public hospital. METHODS: A retrospective, observational, cross-sectional study in adult intensive care unit. Prescribed drugs were collected from medical prescriptions to analyze the occurrence of potential drug interactions and classification, using the database Micromedex® DrugReax®. RESULTS: A total of 289 medical prescriptions and 65.40% of these showed some potential drug interactions. These were classified according to severity in: contraindicated 8 (0.97%), severe 412 (50.25%), moderate 347 (42.32%) and lowest 53 (6.46%). The severity and were grouped according to the documentation available. Potential drug interactions were characterized by risk they involved, including cardiotoxicity and problems related to the central nervous system 57.3% of the 948 identified risks. Were also characterized the management and monitoring strategies for each potential drug interactions identified, and dose adjustment of one or both drugs that interact and monitoring of signs and symptoms frequently with 69.05%. CONCLUSION: The results contribute to the risk profile of the design on the potential drug interactions in intensive care unit and demonstrates the need for performance of clinical pharmacist in this area in order to contribute to the multidisciplinary team in the reduction of risks from therapy drug.
Downloads
Downloads
Published
How to Cite
Issue
Section
License
The authors hereby transfer, assign, or otherwise convey to RBFHSS: (1) the right to grant permission to republish or reprint the stated material, in whole or in part, without a fee; (2) the right to print republish copies for free distribution or sale; and (3) the right to republish the stated material in any format (electronic or printed). In addition, the undersigned affirms that the article described above has not previously been published, in whole or part, is not subject to copyright or other rights except by the author(s), and has not been submitted for publication elsewhere, except as communicated in writing to RHFHSS with this document.
Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License (CC-BY-NC-ND) that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
Serlf-archiving policy
This journal permits and encourages authors to post and archive the final pdf of the articles submitted to the journal on personal websites or institutional repositories after publication, while providing bibliographic details that credit its publication in this journal.
