Performance de trigger tools para triagem de potencial delirium hiperativo em pessoas idosas hospitalizados em departamento de emergência brasileiro

Autores

DOI:

https://doi.org/10.30968/rbfhss.2022.134.0874

Resumo

Objetivo: Avaliar o desempenho de termos trigger tools na detecção de internações de pacientes idosos com potencial delirium hiperativo em uma unidade de emergência. Métodos: Um estudo transversal foi realizado com todos os pacientes com idade ≥ 60 anos internados em unidade de emergência de um hospital universitário brasileiro em 2018. A triagem de potencial delirium hiperativo foi feita com as seguintes trigger tools: prescrição instra-hospitalar de antipsicóticos, códigos do 10° Código Internacional de Doenças (CID-10) proposto pela 5ª edição do Manual Diagnóstico e Estatístico de Transtornos Mentais, e palavras-chave relacionadas com delirium hiperativo registradas em prontuários médicos por profissionais da saúde. O valor preditivo positivo (VPP) foi calculado para avaliar a performance de cada trigger tool. Resultados: A maioria das hospitalizações (192/286) foi triada por pelo menos um dos trigger tools, das quais 49.2% mostrou potencial delirium hiperativo. O trigger tool de CID-10 mostrou uma melhor performance (VPP=0.71), no entanto, essa estratégia subestimou a detecção de casos potenciais [2.6% (5/193)]. A despeito da performance de das prescrições intra-hospitalares de antipsicóticos e palavras-chave ter sido mais baixa (VPP=0.69, e VPP=0.48, respectivamente), a prevalência de potencial delirium hiperativo identificado foi maior com estes métodos [30.0% (58/193); e 47.1% (91/193); respectivamente]. Conclusão: O uso de trigger tools detectou uma a cada três hospitalizações de idosos com potencial delirium hiperativo. A combinação das estratégias pode contribuir para o reconhecimento da síndrome em unidade de emergência. Os dados sugerem que a triagem pode ser realizada por farmacêuticos em associação com abordagens multicomponentes e interprofissionais para melhorar a segurança do paciente.

Downloads

Não há dados estatísticos.

Referências

APS. Diagnostic and Statistical Manual of Mental Disorders (DSM-5®) 5th Edition;2013.

Hshieh TT, Inouye SK, Oh ES. Delirium in the Elderly. Clin Geriatr Med. 2020; 36(2):183-199.

Wilson JE, Mart MF, Cunningham C, Shehabi Y, Girard TD, MacLullich AMJ, et al. Delirium. Nature Sciences 2020; 6:90.

Pérez-Ros P. Martínez-Arnau FM. Delirium assessment in older people in emergency departments. A Literature Review. Diseases. 2019; 7(1):14.

Ahmed S, Leurent B, Sampson EL. Risk factors for incident delirium among older people in acute hospital medical units: A systematic review and meta-analysis.ffects Age Ageing. 2014;43(3):326-33.

Carpinter CR, Hammouda N, Linton EA, Doering M, Ohuabunwa UK, Ko KJ, et al. Delirium Prevention, Detection, and Treatment in Emergency Medicine Settings: A geriatric emergency care applied research (GEAR) network scoping review and consensus statement. Acad Emerg Med 2021; 28(1):19-35

Inouye SK, Westendorp RGJ, Saczynski JS. Delirium in elderly people. Lancet 2014; 383(9920):911-22.

Monette J, Galbaud du Fort G, Fung SH, et al. Evaluation of the Confusion Assessment Method (CAM) as a screening tool for delirium in the emergency room. Gen Hosp Psychiatry. 2001; 23:20–5.]

Han JH, Eden S, Shintani A, Morandi A, Schnelle J, Dittus RS, et al. Delirium in older emergency department patients is na independent predictor of hospital length of stay. Acad Emerg Med. 2011;18(5):451-7.

Shenkin SD, Fox C, Godfrey M, Siddiqi N, Goodacre S, Young J, et al. Delirium detection in older acute medical inpatients: a multicentre prospective comparative diagnostic test accuracy study of the 4AT and the confusion assessment method. BMC Med 2019;17(1):138.

Zalon ML, Sandhaus S, Kovaleski M, Roe-Prior P. Hospitalized older adults with established delirium: recognition, documentation, and reporting. J Gerontol Nurs. 2017;43(3):32-40.

Puelle MR, Kosar CM, Xu G, Schmitt E, Jones RN, Marcantonio ER, et al.The language of delirium: key words for identifying delirium from medical records. J Gerontol Nurs 2015;41(8):34-42.

Zimmerman KM, Paquin AM, Rudolph JL. Antipsychotic prescription to identify delirium: results from two cohorts. Clin Pharmacol. 2017; 9:113-117.

De Wet C, Bowie P. Screening electronic patient records to detect preventable harm: a trigger tool for primary care. Qual Prim Care 2011; 19(2):115–125.

Raso J, Santos LMC, Reis DA, Frangiotti MAC, Zanetti ACB, Capucho HC, et al. Hospitalizations of older people in na emergency department related to potential medication-induced hyperactive delirium: a cross-sectional study. Int J Clin Pharm. 2022; 44(2):548-556.

World Alliance for Patient Safety. Summary of the evidence on patient safety: implications for research. The Research Priority Setting Working Group of the World Alliance for Patient Safety. Geneva:World Health Organization, 2008.

Miguel A, Azevedo LF, Lopes F, Freitas A, Pereira AC. Methodologies for the detection of adverse drug reactions: comparison

of hospital databases, chart review and spontaneous reporting. Pharmacoepidemiol Drug Saf. 2013: 22(1):98-102.

Du W, Pearson SA, Buckley NA, Day C, Banks E. Diagnosis-based and external cause-based criteria to identify adverse drug reactions in hospital ICD-coded data: Application to an Australian population- based study. Public Health Res Pract. 2017;27(2):2721716.

Casey P, Cross W, Mart WS, Baldwin C, Riddell K, P. Hospital discharge data under-reports delirium occurrence: results from a point prevalence survey of delirium in a major Australian health service. Intern Med J 2019;49(3):338-344.

Inouye SK, Leo-Summers L, Zhang Y, Bogardus ST, Leslie DL, Agostini JV. A char-based method for identification of delirium: validation compared with interviewer ratings using de Confusion Assessment Method. J Am Geriatr Soc 2005;53(2):312-8.

Clegg A, Westby M, Young JB. Underreporting of delirium in the NHS. Age Ageing 2011; 40: 283–6.

Kim DH, Lee J, Kim CA, Huybrechts KF, Bateman BT, Patorno E, et al. Evaluation of algorithms to identify delirium in administrative claims and drug utilization database. Pharmacoepidemiol Drug Saf 2017;26(8):945-953.

Hope C, Estrada N, Weir CW, Teng CC, Damal K, Sauer B. Documentation of delirium in the VA electronic health record. BMC Res Notes. 2014; 7:208.

Collins N, Blanchard MR, Tookman A, Sampson EL. Detection of delirium in the acute hospital. Age Ageing 2010; 39:131–5.

Slooter AJC, Otte WM, Devlin JWm Arora RC, Bleck TP, Claassen J, et al. Updated nomenclature of delirium and acute encephalopathy: statement of ten societies. Intensive Care Med.2020; 46(5):1020-1022.

Scottish Intercollegiate Guidelines Network. Risk reduction and management of delirium. 2019. Accessed 25 Mar 2020.

National Institute for Health and Care Excellence (NICE). Delirium: Diagnosis, prevention and management. Clinical Guideline 103. 2010, update March 2019. www.nice.org.uk/CG103. Accessed 25 Mar 2020.

Burry L, Mehta S, Perreault MM, Luxenberg JS, Siddiqi N, Hutton B, et al. Antipsychotics for treatment of delirium in hospitalised non-ICU patients. Cochrane Database Syst Ver 2018;6(6):CD005594.

Yu F, Rafizadeh R, Mabsa VH, Kang N. Risk Evaluation for Antipsychotic Agents Used in Elderly Inpatients (REPAIR). Can J Hosp Pharm2018;71(6):370-375.

Kassie GM, Ellett LMK, Nguyen TA, Roughead EE. Current practice and opinions of hospital pharmacists regarding their role in the screening, prevention and treatment of delirium. Int J Clin Pharm 2017;39(6):1194-1200.

McMaster C, Liew D, Keith C, Aminian P, Frauman A. A machine-learning algorithm to optimise automated adverse drug reaction detection from clinical coding. Drug Saf. 2019;42(6):721-725.

Publicado

2022-12-23

Como Citar

1.
RASO J, SANTOS LM, REIS DA, FRANGIOTTI MA, ZANETTI AC, CAPUCHO HC, HERDEIRO MT, ROQUE F, LEIRA-PEREIRA LR, VARALLO FR. Performance de trigger tools para triagem de potencial delirium hiperativo em pessoas idosas hospitalizados em departamento de emergência brasileiro. Rev Bras Farm Hosp Serv Saude [Internet]. 23º de dezembro de 2022 [citado 16º de julho de 2024];13(4):874. Disponível em: https://rbfhss.org.br/sbrafh/article/view/874

Edição

Seção

ARTIGOS ORIGINAIS

Artigos mais lidos pelo mesmo(s) autor(es)