Major drug interactions in patients adult intensive care unit of a private hospital Minas Gerais
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Palavras-chave: Interação Medicamentosa; Prescrições, Medicamentos; UTI.Abstract
Objective: Knowing the profile of drug interactions with the requirements of the Intensive Care Unit Adult (AICU).
Methods: During the analysis of 211 prescriptions of UTIA drugs were divided into two classes: medicines used for treatment and drugs used for palliative care, defined according to the diagnosis of pathology of the patient who is hospitalized in UTIA. The most commonly prescribed drugs used in treatment were crossed with each other and with the most commonly used drugs for palliative care in search of possible drug interactions.
Results: In 30% of prescriptions were found interactions of high severity (enoxaparin and clopidogrel) and 70% interactions of moderate severity (simvastatin and clopidogrel).
Conclusion: The recognition of possible drug interactions avoid treatment failure or minimize the appearance of drug toxicity, by adjusting the regimen or the use of alternative drugs.
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