Interference of the tamoxifen dispensing system in the adherence to pharmacotherapy of women with breast cancer
DOI:
https://doi.org/10.30968/rbfhss.2023.142.0872Abstract
Objectives: To evaluate the medication adherence of women with breast cancer undergoing treatment with tamoxifen, before and after the change in the frequency of medication dispensing from monthly to quarterly, to elucidate the influence of this factor on adherence to therapy. Methods: A prospective, quantitative, cross-sectional, interview-type field study was carried out from the collection of data from women with breast cancer, on hormone therapy with tamoxifen, treated at an oncology hospital in the State of Paraná, Brazil. At first, a questionnaire of sociodemographic and clinical data was applied to characterize the patient in the sample and, also, the adherence to refills and medications scale (ARMS) instrument to assess adherence to treatment. The ARMS questionnaire was applied a second time, after changing the medication from monthly to quarterly dispensing. Results: Thirty patients is an interviewed, with a mean age of 54 years and most of them (80%) were in the initial stage at diagnosis. In the first interview, 66% had already undergone chemotherapy and radiotherapy, 86% had a record of tumors in the family and the average time of treatment with tamoxifen was 22 months. The mean adherence score obtained by ARMS in the first interview was 13.2 ± 1.52 (12 to 48 points) and 13.3 ± 1.73 in the second interview. Conclusions: There was no significant difference in the adherence score to tamoxifen treatment before and after changes in the frequency of dispensing.
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