Pharmaceutical recommendations in a university hospital transplant unit


  • Maria K. Pinheiro
  • Elana F. Chaves
  • Alene B. Oliveira
  • Cinthya C. Andrade
  • Katherine X. Bastos
  • Marjorie M. Guedes



Introduction: The transplanted patient has a complex pharmacotherapy, with the pharmacist having an important role in the multidisciplinary team. Objective: To analyze the pharmaceutical recommendations made during the hospitalization of the patients in kidney and liver transplant units. Methods: This was a cross-sectional study in which pharmaceutical recommendations from May 2017 to April 2018 were collected from the records contained in the database of the Clinical Pharmacy Unit of a University Hospital in Fortaleza, Brazil. The recommendations were categorized and analyzed based on the classification used in the institution. Results: There were 1241 pharmaceutical recommendations involving 325 patients and 1466 medications. The recommendations were more frequent during liver transplantation (54.2%, n = 672), with dose adjustments (18.2%, n = 122) and dilution / reconstitution (9.8%, n = 66) being the most predominant types. In kidney transplantation, recommendations for education about medication use (17.6%, n = 100) and treatment adherence strategies (17.6%, n = 100) were the most predominant. The most frequent therapeutic classes were systemic antibacterials (31.2%, n = 458) and immunosuppressants (25.1%, n = 368). The acceptance rate of recommendations for kidney and liver transplantation were 95.1% (n = 541) and 95.4% (n = 641), respectively. Conclusions: The present study showed a high frequency of pharmaceutical recommendations and these results demonstrate that the detection of drug-related problems generates pharmaceutical recommendations that can contribute to the reduction of negative drug-associated results and increase patient safety.


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How to Cite

Pinheiro MK, Chaves EF, Oliveira AB, Andrade CC, Bastos KX, Guedes MM. Pharmaceutical recommendations in a university hospital transplant unit. Rev Bras Farm Hosp Serv Saude [Internet]. 2019Dec.31 [cited 2024Apr.21];10(4):361. Available from:




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