Evaluation of the use of antimicrobial in a specialized traumatology and orthopedics public hospital

  • MAELY PEÇANHA FÁVERO RETTO
  • MARCELE LIMA MONTE GONÇALVES
  • ISABELA AZEVEDO MOTA
  • MICHELLE ARAÚJO DE LIMA MAGALHÃES
  • NATÁLIA REGINA DE SOUZA PEREIRA
  • ISABELA LAUDARES MARQUES

Abstract

Purpose: This study describes and evaluates the use of systemic antimicrobials in a orthopedic surgeries specializing hospital.

Methodology: By means of a retrospective descriptive study in a orthopedic surgeries specializing hospital with data from 2006 to 2010, described the profile of Antimicrobial use through calculation of defined daily dose (DDD) per 100 hospital beds days using the classification DDD / ATC of the World Health Organisation for anti-infective drugs, in addition to data on active hospital beds and annual occupancy rate achieved from the management system of the hospital. For the analysis of the data it was collected information about infection rates, mean length of stay, number of patients admitted, and transfers made patients in use of antimicrobials.

Results: 9.61 ± 0.44% of hospitalized patients used systemic antimicrobials. Oxacillin, ciprofloxacin and vancomycin had higher DDD/100 hospital beds day, 26.90 ± 4.21, 15.70 ± 3.14 and 6.75 ± 1.55 respectively. In 2008 Cefazolin had decrease consumption, since it is now recommended as prophylactic use of antibiotics in orthopedic surgeries. There was an increase in the consumption of carbapenems in recent years, parallelly the reduction of cephalosporins.

Conclusion: The profile of antimicrobials consumption drawn from this study is consistent with lots of data presented in the literature and what recommended clinical protocols. It was possible to evaluate the variation of the use of this drug class and setting turns of antimicrobial uses in order to prevent selective pressure on microorganisms and the subsequent development of resistance. 

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Published
2019-03-11
How to Cite
RETTO, M. P. F., GONÇALVES, M. L. M., MOTA, I. A., MAGALHÃES, M. A. D. L., PEREIRA, N. R. D. S., & MARQUES, I. L. (2019). Evaluation of the use of antimicrobial in a specialized traumatology and orthopedics public hospital. Revista Brasileira De Farmácia Hospitalar E Serviços De Saúde, 7(4). Retrieved from https://rbfhss.org.br/sbrafh/article/view/277
Section
ARTIGOS PUBLICADOS