Dose adjustment in the use of vancomycin in the pediatric icu of a university hospital in Porto Alegre

Authors

  • VIVIAN ANDREA ASEFF LANES
  • ANA LIGIA BENDER
  • MAYARA BECKER DELWING

Abstract

To  assess  kidney  function  and  serum  levels  as  reasons  for  vancomycin  dose  adjustment  in  patients  admitted  to  the  Pediatric  Intensive  Care  Unit  of  a  university  hospital  in  Porto  Alegre.  We  conducted  a  retrospective descriptive study of patients who used vancomycin in the period from 1 April 2013-28 February 2014.  Data  were  analyzed  using  Pearson  correlation  coefficient.  The  level  of  significance  was  5%  (p  <0.05).  Analyses were performed using SPSS, version 20. We studied 66 treatments with vancomycin performed for 61  patients.  Among  the  main  results  showed  that  dose  adjustments  are  related  to  the  days  of  vancomycin  use  and  hospital  stay  and  intensive  care  unit,  among  others.  Dose  adjustment  in  antibiotic  therapy  with  vancomycin  ensures  patient  safety.  The  pharmacist’s  inclusion  in  the  multidisciplinary  team  prevents  errors  related to its use and therefore reduces the risk to the patient and hospital costs.

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Published

2019-03-11

How to Cite

1.
LANES VAA, BENDER AL, DELWING MB. Dose adjustment in the use of vancomycin in the pediatric icu of a university hospital in Porto Alegre. Rev Bras Farm Hosp Serv Saude [Internet]. 2019Mar.11 [cited 2022Nov.30];7(3). Available from: https://rbfhss.org.br/sbrafh/article/view/261

Issue

Section

ARTIGOS PUBLICADOS