Pharmacotherapy of patients in substitutive renal therapy: an adherence approach
Keywords:perfil farmacoterapêutico; adesão medicamentosa; insuficiência renal crônica.
To evaluate the pharmacotherapeutic profile and adherence in patients with chronic renal failure undergoing dialysis from a large hospital in the Midwest of Minas Gerais, Brazil. This is a cross-sectional study carried out in a philanthropic hospital during the dialitic session. The Morisky Medication Adherence Scale - 4 items (MMAS-4) and Brief Medication Questionnaire (BMQ) were used to analyze the patient adherence additionally the presence of polypharmacy and the therapeutic complexity index were assessed. 219 patients were include, characterized by predominantly male, white, married and mean age of 56.5 years old (SD:13.2). The main classes of medications in use were antihypertensive and phosphorus binders and 66% of participants presented polypharmacy and therapeutic complexity was considered high. Neither polypharmacy or adherence are influenced by social factors (gender, ethnicity, retirement or health care insurance). Adherence profile by MMAS-4 corresponded to high adherence in 50.5% while by the BMQ corresponded to likely poor adherence in 80.6%. Both tests agreed concerning low adherence profile). The pharmacotherapy of patients with chronic renal failure undergoing dialysis is complex and adherence may variety according to the test used.
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