Interaction between serotonin reuptake inhibitors and tamoxifen: a literature review

Authors

  • MAIARA PRISCILA DOS PASSOS
  • FLAVIA VALLADÃO THIESEN
  • ANA PAULA DUARTE DE SOUZA
  • LUCIANA MELLO DE OLIVEIRA

Keywords:

Tamoxifeno, Depressão, Agentes antidepressivos.

Abstract

To performe a literature review of clinically relevant drug interactions with the concomitant use of tamoxifen  and  serotonin  reuptake  inhibitors.  A  keyword  research  was  conducted  using  the  terms  “drug  interactions,”  “tamoxifen,”  and  “depression”  in  the  PUBMED  database;  “antidepressive  agents,”  “antidepressants,”  and  “tamoxifen”  in  LILACS;  “tamoxifen,”  “drug  interactions,”  and  “depression”  in  EMBASE.  Studies  published  from 2005 to 2015, in Portuguese, English, and Spanish were considered.The research returned 80 articles. Duplicates and articles that did not meet research criteria were excluded. As result, 14 articles were considered for this study.There  is  an  clinically  relevant  interaction  between  serotonin  reuptake  inhibitors  and  tamoxifen.  The  concomitant use of both drugs should be avoided in order to prevent serious side effects.  

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Published

2019-03-11

How to Cite

1.
PASSOS MPD, THIESEN FV, SOUZA APDD, OLIVEIRA LMD. Interaction between serotonin reuptake inhibitors and tamoxifen: a literature review. Rev Bras Farm Hosp Serv Saude [Internet]. 2019Mar.11 [cited 2024Feb.25];7(1). Available from: https://rbfhss.org.br/sbrafh/article/view/246

Issue

Section

ARTIGOS PUBLICADOS