Study adaptations of pharmaceutical formulations in a university children's hospital
Keywords:Pediatria, Adaptações farmacêuticas, Farmacotécnica.
AIM: The aim of this study was to analyze the incidence of adaptations on pharmaceutical products (breaking and /or grinding tablets, opening capsules or dilution of oral liquid formulations available only in high concentrations) in a university pediatric hospital. These results will serve as an incentive for the development of hospital pharmacotechnical services or outsourcing of pediatric formulations. METHODS: This is an exploratory documental research which has transversal, prospective, descriptive and observational delineation. It was performed from June 1 to August 31, 2013. The copies of prescriptions of the hospitalized patients were examined and medicines and types of adaptations were identified and quantified to determine the frequency and the motivating factors. RESULTS: A total of 2,270 requirements were evaluated. From these, 1,505 were subjected of pharmaceutical adaptations. The group of patients of age from 0 - | 7 years was the most representative regarding the number of adaptations. Grinding tablets was the most performed procedure in order to facilitate the administration and 60.6% of the adaptations occurred because of the necessity to administer drugs available only in high concentrations. Furosemide (20.9%), calcium carbonate (10.9%) and folic acid (8.5%) were the drugs with higher solicitation of adapted formulations. CONCLUSION: This study confirmed the lack of formulations suitable for pediatric concentrations, ratifying the need for a pharmacotechnical service in a hospital setting.
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