Drug interactions among the most prescribed drugs in adult intensive care unit
Keywords:Interação medicamentosa, medicamentos, prescrições, UTI.
Objective: To identify the most prescribed drugs and their drug interactions in Intensive Care Units (ICU), adding knowledge to the health care team. Methodology: This observational retrospective and descriptive study was carried out in Cardiologic and General ICUs of a Hospital in the countryside of São Paulo, analyzing the medical prescriptions from January to March 2015, of patients with more than 18 years, both sexes, with length of hospital stay higher than 24 hours and that had at least two drugs prescribed, excluding urgency specifications and additions. The study identified the most prescribed drugs, the potential drug interactions among them and classified them as to their degree of severity. Results: Of the 211 prescriptions analyzed, 150 (71,1%) showed some interaction between the most prescribed drugs. In 7,6% of the prescriptions, drug interactions of greater severity were found, in 60,2%, interactions of moderate severity, in 3,3%, less severe interactions, and 28,9% of the prescriptions did not show interactions between the most prescribed drugs. Conclusion: The results obtained in this study help the assessment of the medical prescriptions in ICUs, contributing to the health teams in order to reduce the risks arising from drug therapy and optimize the desired results.
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