Dose unitarization and patient’s safety: hospital pharmacy’s or drug industry’s responsibility?
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Descritores: sistemas de dispensação de medicamentos, Sistema de Distribuição de Medicamentos por Dose Unitária, serviços de farmácia hospitalar, indústria farmacêuticaAbstract
Objective: This study aims at performing a literature-based critical analysis about medication dispensing systems, considering fractionation of primary package, tracking, supervision, and current legislation.
Methods: Descriptors in Portuguese and their correspondents in Spanish and English (hospital pharmacy service, distribution system, health surveillance, and pharmaceutical legislation for hospital and industry areas) were used on Health Virtual Library (BVS/BIREME) database and on Health Surveillance National Agency (ANVISA) website.
Results: Our revision analyzed 6 current legislations and 18 articles in Portuguese, Spanish, or English, that addressed hospital pharmacy activities directed to the safety of hospitalized patients, considering unit dose drug distribution system, error causes in distribution system, and current legislation, published after 2005.
Conclusion: Our analysis identified that some individual failures could be minimized if the legislative bodies formulate laws to obtain an effective service for the patient’s safety, avoiding the lack of organizational safety and applying more effective strategies to reduce the error consequences.
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