Acute kidney injury in critical patients: profile clinical and relationship with serious processes infectious

Abstract

To establish a common clinical profile of the patients who developed AKI during hospitalization in the intensive care unit and its relation to serious infections. Cross-sectional observational study carried out in the general intensive care unit of the Hospital Municipal São José. We included all patients over 18 years admitted during the period from May to September 2015. Patients who had prior kidney damage and less hospitalization than 48 hours were excluded. Data were collected on risk factors for development of renal injury, severity scores of critical patients, antibacterial therapy administered and classification of renal injury when detected. The data was collected in electronic medical records daily. Data were presented as mean ± standard deviation, or percentage of registered parameters. 37 patients were included, mean age 46.6 years, 26 men. Risk factors found were more hypertension and diabetes mellitus. The mean SAPS 3 scores were 67,20 e 61,89 to patients with and without acute kindey failure, respectively and to the SOFA score, 9,80 e 6,94, respectively. It was observed that the group affected by acute kidney injury had proportionally higher number of cases of sepsis and more nephrotoxic antibacterial associations as treatment. Among patients with acute kidney injury, more than half showed significant renal impairment, according to the AKIN classification. Patients who received more antibacterial compounds, and were exposed to septic episodes, perhaps are more vulnerable to the development of acute kidney injury.